Effects of Jiang Zhi Tong Luo Soft Capsule and rosuvastatin on type 2 diabetes combined with hyperlipidemia
10.3969/j.issn.1671-8348.2015.24.012
- VernacularTitle:降脂通络软胶囊联合瑞舒伐他汀对2型糖尿病合并高脂血症患者效果观察?
- Author:
Hui GUO
;
Liangzhuan LIU
;
Jianghua LIU
- Publication Type:Journal Article
- Keywords:
diabetes mellitus,type2;
hyperlipidemia;
Jiang Zhi Tong Luo Soft Capsule(JTSC);
rosuvastatin
- From:
Chongqing Medicine
2015;(24):3348-3349
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of combined administration of Jiang Zhi Tong Luo Soft Capsule(JTSC)and rosu-vastatin on type 2 diabetic with hyperlipemia and its possible mechanisms.Methods Eighty cases of Type 2 diabetic patients with hyperlipemia were divided into combine treatment group (40 cases)and control group (40 cases ).On the basis of routine treat-ment,patients in the combine treatment group were treated by oral 10 mg rosuvastatin (once a day)and oral 100 mg JTSC (three times a day ).Patients in control group were treated by oral 10 mg rosuvastatin (once a day and continuously for 12 weeks).We de-tected the liver function,renal functions,creatine kinase,TC,TG,LDL,HDL and hs-CRP were tested before and after treatments. Results After 12 weeks treatment,the combine treatment group was much better than the control group in reducing the level of TG,TC,LDL,hs-CRP and increasing HDL-C(P <0.05 ).Conclusion Rosuvastatin can effectively treat Type 2 diabetic patients with hyperlipemia.Combined administration of JTSC and rosuvastatin shows better effect than rosuvastatin used alone on the treat-ment of Type 2 diabetic patients with hyperlipemia.