The clinical significance of plasma D-dimer in lung cancer and pulmonary tuberculosis
10.3969/j.issn.1673-4130.2015.15.001
- VernacularTitle:肺癌和肺结核患者血浆中D-二聚体检测的临床意义
- Author:
Yong SUN
;
Xiangyu DING
;
Baoqiu ZHANG
;
Xueyu WANG
;
Xiuli GOU
;
Jie ZHANG
;
Guangli SHI
- Publication Type:Journal Article
- Keywords:
D-dimer;
lung cancer;
pulmonary tuberculosis
- From:
International Journal of Laboratory Medicine
2015;(15):2129-2130
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the plasma levels of D‐dimer in lung cancer and pulmonary tuberculosis (PTB) patients and their clinical significances .Methods The plasma of 130 patients with lung cancer ,126 patients with PTB and 50 healthy controls were collected .All the patients were enrolled in Beijing Affiliated to Chest Hospital Capital Medical University ,from July 2014 to October 2014 .Full‐automatic analyzer was used to examine the level of plasma D‐dimer .Results The levels of plasma D‐dimer in patients with lung cancer were significantly higher than patients with PTB and healthy controls (Z=2 .704 ,P<0 .01);The levels of plasma D‐dimer in patients with PTB were significantly higher than healthy controls (Z=2 .54 ,P<0 .05);The levels of plasma D‐dimer were significantly higher in stages Ⅲ and Ⅳ than stages Ⅰ and Ⅱ(Z=2 .195 ,P<0 .05);The positive rate in patients with lung cancer was significantly higher than patients with PTB (χ2 =10 .525 ,P<0 .01) .Conclusion Activation of coagulation and fi‐brinolysis exist in lung cancer and PTB patients ,the level of plasma D‐dimer is related to the clinical stage of lung cancer .
