Clinical application of LI-RADS in diagnostic evaluation of hepatocellular carcinoma
10.3969/j.issn.1002-1671.2015.08.011
- VernacularTitle:运用肝脏影像报告和数据管理系统评价肝细胞肝癌的临床研究
- Author:
Junqiang LEI
;
Pin YANG
;
Mengshu WANG
;
Jinkui LI
;
Ruifeng YAN
;
Changqin JIANG
;
Feilong LI
;
Kehu YANG
- Publication Type:Journal Article
- Keywords:
liver imaging reporting and data system;
hepatocellular carcinoma
- From:
Journal of Practical Radiology
2015;(8):1278-1282
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the reliability and validity of hepatocellular carcinoma (HCC)using the liver imaging reporting and data system (LI-RADS).Methods By using the LI-RADS v2013.1,two radiologists evaluated 1 62 patients with cirrhosis or with a risk of HCC according to an inclusion criteria.The Kappa value was used to evaluate the consistency between two different diagnoses and was compared with pathological and follow-up results.The accuracy of the LI-RADS was assessed including sensitivi-ty,specificity,positive predictive value,negative predictive value,positive likelihood ratio,negative likelihood ratio and accuracy rating.Results In all 1 62 patients,there were HCCs in 97 patients including 7 patients belonging to the LR3,benign diseases in 50,and other kinds of malignancy in 1 5.The Kappa value was 0.882 (P =0.000)between two observers on LI-RADS grading. The sensitivity,specificity and accuracy rating of LI-RADS grading in diagnosing HCC was 100.00%,91.30%,and 97.06%,re-spectively.Conclusion The LI-RADS has high consistency and stability in evaluation and diagnosis of HCC by enhanced CT.LR3 di-agnosis should be cautious because of a susceptible development to HCC,which can be improved through the combination of clinic and laboratory examination.
