Analysis and comparison in optimized treatment of chronic recurrent hepatitis C

VernacularTitle:慢性复发性丙型肝炎的优化治疗疗效分析与比较
Author: Yan FANG ; Qiongfang ZHANG ; Dazhi ZHANG
Publication Type:Journal Article
Keywords: recurrent hepatitis C; optimal treatment; recurrence rate; efficacy
From: Chongqing Medicine 2015;(23):3218-3220
CountryChina
Language:Chinese
Abstract: Objective To optimize the treatment of chronic hepatitis C recurrence.Methods During May 2008 to May 2012, 50 patients with chronic recurrent hepatitis C were chosen in the infectious department of our hospital.They were divided into two groups with 25 cases in each group.Group A was treated by standard extended treatment scheme,while Group B was treated by standard large dose scheme.The effect was estimated by the observation of sustained virologic response in the two groups (sus-tained virologic response,SVR).Results 32% SVR rate was found in group A and 23% SVR rate was found in Group B.38% re-currence rate appeared in group A after six months and 43% recurrence rate occurred in group B,there were significant difference between two groups(P <0.05).Conclusion The standard extended treatment schemes of pegylated interferon and ribavirin is su-perior to group B in SVR rate.