The role of RF,CRP,ESR in the diagnosis of rheumatoid arthritis
10.3969/j.issn.1673-4130.2015.20.036
- VernacularTitle:类风湿因子、快速C反应蛋白、红细胞沉降率诊断类风湿关节炎的价值
- Author:
Xuming ZHU
;
Xiaoqing DING
;
Yan YANG
- Publication Type:Journal Article
- Keywords:
rheumatoid arthritis;
rheumatoid factors;
C-reactive protein;
erythrocyte sedimentation rate
- From:
International Journal of Laboratory Medicine
2015;(20):3007-3008
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of rheumatoid factor(RF) ,C‐reactive protein(CRP) ,erythrocyte sedimentation rate (ESR) in the diagnosis of rheumatoid arthritis(RA) .Methods 74 RA patients and 90 patients with symptoms similar to RA were recruited in the study randomly .Blood samples were detected for the levels of RF ,CRP ,ESR .The results were compared between two groups .Receiver operating characteristic curve(ROC) was used to access the diagnostic efficiency .Results The levels of RF , CRP ,ESR of RA group were (271 .4 ± 560 .9)IU/mL ,(28 .7 ± 35 .6)mg/L ,(60 .9 ± 40 .1)mm/h ,respectively ,and were higher than those of control group which were (56 .8 ± 189 .3)IU/mL ,(15 .4 ± 24 .7)mg/L ,(45 .1 ± 33 .1)mm/h respectively .ROC analysis re‐vealed that the AUC of RF ,CRP ,ESR and combined detection of the 3 factors were 0 .784 ,0 .666 ,0 .615 ,0 .757 ,respectively with statistical significance(P<0 .05) .Conclusion RF ,CRP ,ESR are useful in the diagnosis of RA ,and RF has the highest diagnostic ef f iciency .
