Factors affecting mean blood glucose level of newly diagnosed type 2 diabetes pa-tients
10.3969/j.issn.1000-4718.2015.10.006
- VernacularTitle:新诊断2型糖尿病患者平均血糖的相关因素分析
- Author:
Sihui LUO
;
Hongrong DENG
;
Xubin YANG
;
Donge GONG
;
Jinhua YAN
;
Yanhua ZHU
;
Wen XU
;
Jianping WENG
- Publication Type:Journal Article
- Keywords:
Type2diabetesmellitus;
HemoglobinA1c;
Continuousglucosemonitoringsystem;
Bloodglucose
- From:
Chinese Journal of Pathophysiology
2015;(10):1762-1766
- CountryChina
- Language:Chinese
-
Abstract:
AIM:TodetecthemoglobinA1c(HbA1c)andparametersofbloodglucosefluctuationinChinesenewlydiag-nosed type 2 diabetes mellitus (T2DM) patients, and further to specify the factors that were related to mean blood glucose (MBG) in this population.METHODS:Newly diagnosed T2DM patients (n=90) from 4 hospitals in Guangdong province were enrolled, and subjected to 3 d continuous glucose monitoring (CGM) after testing for HbA1c and other laboratory tests.Blood glucose data collected during CGM were used to calculate MBG and parameters of blood glucose fluctuation.RESULTS: Correlation analysis revealed that MBG was significantly related to all parameters of blood glucose fluctuation, HbA1c, fast plasma glucose ( FPG) and 2 h postprandial glucose (P<0.01), but not to sex, age or blood lipid profile.Further analysis utilizing step-wise general linear model showed that HbA1c, absolute means of daily difference ( MODD) , difference between maximal and minimal glucose ( DMMG) and FPG had the strongest relation to MBG.CONCLUSION: Factors affecting MBG of the newly diagnosed T2DMpatients in our country include HbA1c, FPG, DMMG and MODD, and thus it may be prone to misleading results that only HbA1c is applied to estimate MBG in this population.
