Experimental study of antimicrobial formulas in wet honey ice bedsores
- VernacularTitle:褥疮冰蜜湿敷剂中组方药的抗菌实验研究
- Author:
Junying RAO
;
Zhi HAN
;
Bicheng JIN
;
Yaoyong ZHANG
;
Yan ZHOU
- Publication Type:Journal Article
- Keywords:
wet honey ice bedsores;
formulas;
bedsore;
colony count;
rabbit
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(8):52-54
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study antibacterial effect of formulas, borneol, honey, gentamicin in wet honey ice bedsores.Methods The third-stage infective bedsore model in rabbit were estabished with Staphylococcus aureus ( S.aureus) , Escherichia coli ( E.coli) , and Pseudomonas aeruginosa ( P. aeruginosa).The rabbits with bedsore were respectively compressed with gauze of honey+borneol, honey+gentamicin,borneol+gentamicin,borneol+gentamicin+honey, vaseline as control group.The strain identification and colony counts were observed before and after treatment.ResuIts The colony count of S.aureus, E.coli and P.aeruginosa in honey+borneol, honey+gentamicin, borneol+gentamicin, borneol+gentamicin+honey post-treatment was significantly higher than that of pre-treatment, respectively (P<0.05).The colony count of three strains in above four formulas post-treatment was significantly lower than that in vaseline group, respectively (P <0.05).The colony count of three strains in borneol +gentamicin +honey (original formula) post-treatment was significantly lower than that in the other formulas, respectively (P<0.05).ConcIusion The antibacterial effect of borneol+gentamicin+honey (original formula) is the best.
