Comparison of Micromeritics Properties and External Dissolution Rates ofSanhuang Powder with Different Particle Sizes
10.3969/j.issn.1005-5304.2015.09.025
- VernacularTitle:不同粒径三黄粉粉体学性质及体外溶出度比较
- Author:
Lingyun FAN
;
Zhenheng WANG
;
Yan YU
;
Jiande GAO
;
Shuchang WEI
- Publication Type:Journal Article
- Keywords:
Sanhuang Powder;
superfine grinding;
micromeritics property;
hygroscopicity;
external dissolution rate
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2015;(9):91-94
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the micromeritics properties and external dissolution rates of Sanhuang Powder in different particle sizes;To provide references for its direct use and application as raw materials for TCM preparation.Methods Particle size, bulk density, tap density, angle of repose, and hygroscopicity ofSanhuang micro-powder and common powder were investigated and evaluated. External dissolution rates ofSanhuang micro-powder and common powder were detected by ultraviolet spectrophotometry.Results The flowability of bothSanhuang micro-powder and common powder were not very well. With the sizes decreasing, the hygroscopicity of micro-powder became stronger. The external dissolution ofSanhuang micro-powder was more sufficient and much more quickly than common powder.Conclusion Properties ofSanhuang micro-powder and common powder are obviously different.Sanhuang micro-powder has stronger hygroscopicity and worse flowability compared with common powder. However, external dissolution ofSanhuang micro-powder is more sufficient and much more quickly than common powder. WhenSanhuang micro-powder is used directly and used as raw materials for TCM preparation, much more discretion should be considered.
