Laboratory diagnostic value of COPD with congestive cardiac failure
10.3969/j.issn.1673-4130.2015.15.026
- VernacularTitle:慢性阻塞性肺病合并充血性心力衰竭的实验室诊断价值的探究
- Author:
Kuan PENG
;
Xiaojuan WANG
- Publication Type:Journal Article
- Keywords:
chronic obstructive pulmonary disease with congestive cardiac failure;
B-type natriuretic peptide;
hyper-sensi-tive C reactive protein;
hemoglobin
- From:
International Journal of Laboratory Medicine
2015;(15):2187-2188
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the Laboratory diagnostic value of COPD with congestive cardiac failure .The clinical signif‐icance on the combined detection of the serum B‐type natriuretic peptide(BNP) ,high sensitive C reactive protein (hs‐CRP) ,and he‐moglobin(Hb) in COPD with congestive cardiac failure .Methods The serum levels of BNP ,hs‐CRP and Hb in 205 patients with different etiological factors and grades(according to the pulmonary function test Ⅰ - Ⅳ) and 100 healthy controls were determined . The sensitivity and specificity of 3 parameters were evaluated .Results The levels of BNP ,hs‐CRP ,and Hb in different grades of COPD had statistical significance(P<0 .05) .In addition ,the grade was worse ,and its concentration was higher .The levels of BNP and Hb showed statistical significance between COPD I grade patients and healthy controls (P<0 .05) ,and the levels of hs‐CRP had no statistical significance between the healthy controls and COPD Ⅰgrade patients(P>0 .05) .The sensitivity of combined detection was 90 .2% in early COPD diagnosis ,which was higher significantly than that of the individual detection (P<0 .05) .Conclusion The significant clinical significance on the combined detection of the serum BNP ,hs‐CRP and Hb provides reference support in the diagnosis of early COPD .
