A relationship between the brain magnetic resonance imaging of optic nerve myelitis patients and their CSF biochemical indexes
10.3760/cma.j.issn.1008-6706.2015.16.010
- VernacularTitle:视神经脊髓炎脑脊液生化指标及颅脑磁共振影像学的关系
- Author:
Xiaowen YU
;
Xiaoqing WANG
;
Wenjun ZHANG
;
Xiping TUO
- Publication Type:Journal Article
- Keywords:
Neuromyelitis optica;
Magnetic resonance imaging;
cerebrospinal fluid
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(16):2431-2433
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare differences of CSF biochemical index in optic myelitis combined with abnormal signal in craniocerebral MRI with no significant abnormalities in brain MRI.Methods The data of 39 cases who meet the diagnostic criteria of Wingerchuck were collected.The brain MRI and cerebrospinal fluid,blood bio-chemical indexes were retrospectively analyzed.Results There were no statistical differences between two groups of patients in onset age,average age,hospitalization days,the number of red blood cells,white blood cell,hemoglobin, cerebrospinal fluid leukocyte and CSF synthetic index,the total number of cells,cerebrospinal fluid IgG,synthetic rate index of sheath,but the index of blood brain barrier(CSF:serum albumin ratio,AR)of NMO patients with craniocere-bral MRI abnormalities was higher than normal group(P <0.05).Conclusion NMO patients with brain abnormali-ties are common,and cerebral MRI with signs of abnormalities shows a higher AR value,speculated that abnormal brain MRI signal in NMO patients is associated with the damage of blood -brain barrier,investigation of NMO brain MRI performance can improve the diagnosis of the NMO and identification with multiple sclerosis.
