Effect ofQi-reinforcing and Blood-activating Medication on Tumor Angiogenesis
10.11842/wst.2015.06.032
- VernacularTitle:补气活血药对肿瘤血管生成的影响*
- Author:
Wenhua ZANG
;
Lin ZHI
;
Decai TANG
- Publication Type:Journal Article
- Keywords:
Qi-reinforcing and blood-activating medication;
Chinese medicine compatibility;
tumor;
angiogenesis;
vascular endothelial cell
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2015;(6):1300-1304
- CountryChina
- Language:Chinese
-
Abstract:
Angiogenesis is an important link of tumor growth, invasion and metastasis. The tumor angiogenesis targeting strategy for the treatment of cancer has become a hot spot in oncology research currently. Signal transduction of tumor angiogenesis is a complex, multi-factor, multi-way and cross network system. Treatment for a single target is often not sufficient to halt or reverse its highly heterogeneous structure and abnormal shape. Therefore, it will be an important research direction that the combination of different pathways and mechanisms of medications effect on signaling pathway in tumor angiogenesis by multi-target. A number of experimental studies found that qi-reinforcing and blood-activating medication can play a regulating role of multiple targets, multiple pathways in tumor angiogenesis. It had different effect on tumor angiogenesis against tumor invasion and metastasis.Qi-reinforcing and blood-activating medication will have broad prospects in the treatment of tumor and angiogenesis.