Extraction of Paeoniflorin and Its Derivatives fromGui-Zhi Fu-Ling Capsule Using Molecular Imprinting Technology

VernacularTitle:分子印迹技术分离桂枝茯苓胶囊中芍药苷类活性组分成分＊
Author: Rui GU ; Shiping LI ; Fuyong NI ; Yiwu ZHAO ; Liang CAO ; Wenzhe HUANG ; Zhenzhong WANG ; Xiaojie XU ; Wei XIAO
Publication Type:Journal Article
Keywords: Molecular imprinted technology; sol-gel process; paeoniflorin; Gui-Zhi Fu-Ling Capsule
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(5):1051-1055
CountryChina
Language:Chinese
Abstract: Paeoniflorin and its derivatives are main active compounds inGui-Zhi Fu-Ling Capsule (GZFLC). In this study, molecular imprinted polymer (MIP) was prepared by sol-gel process to obtain paeoniflorin and its derivatives in GZFLC. The static adsorption capacity of MIP was measured by scatchard equation. The results showed that the maximum apparent absorbing capacity of MIP was 52.28 mg·g-1. One-step separation of paeoniflorin from 4 g methanol samples of GZFLC was 197 mg with the purity of 89.3%. It was concluded that paeoniflorin MIP can be used to separate phaoniforin and its analogues from GZFLC.