Advances in signaling pathways of pancreatic cancer
10.3969/j.issn.1000-8179.20150613
- VernacularTitle:胰腺癌细胞信号传导机制的研究进展
- Author:
Dalu KONG
;
Qiang LI
- Publication Type:Journal Article
- Keywords:
pancreatic cancer;
signaling pathways;
transduction
- From:
Chinese Journal of Clinical Oncology
2015;(14):724-727
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic cancer has a very poor prognosis, with a five-year survival less than 5%. Nowadays, to improve the treat-ment efficacy of pancreatic cancer has been a highlight for medical researchers worldwide. Increasing knowledge about the molecular pathogenesis of the disease has shown that genic mutations, such as oncogene Kras2, and anti-oncogenes Cdkn2a, and TP53, are hall-marks of pancreatic cancer. Therefore, it is vital to deeply understand the pathogenetic mechanism of pancreatic cancer and find new therapeutic strategies to cover it. In this review, we summarized the recent advances in the signaling pathways of pancreatic cancer.
