Study on Nephrotoxicity of Aristolochic Acid in Traditional Chinese Medicine
10.11842/wst.2015.05.033
- VernacularTitle:中药马兜铃酸的肾毒性研究
- Author:
Wenting LI
;
Mianhua WU
- Publication Type:Journal Article
- Keywords:
Aristolochic acid;
aristolchic acid nephropathy;
nephrotoxicity;
research progress
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2015;(5):1095-1099
- CountryChina
- Language:Chinese
-
Abstract:
This paper was aimed to discuss the mechanism of aristolchic acid toxicity, pathogenesis and possible causes of aristolchic acid nephropathy. Recent published studies both at home and abroad were summarized on the impact of aristolchic acid on the incidence and progression of aristolchic acid nephropathy. The results showed that traditional Chinese medicine (TCM) containing aristolchic acid was closely associated with the incidence of aristolchic acid nephropathy. It was concluded that the paper provided some suggestions on preventing aristolchic acid nephropathy.