Study on Nephrotoxicity of Aristolochic Acid in Traditional Chinese Medicine

VernacularTitle:中药马兜铃酸的肾毒性研究
Author: Wenting LI ; Mianhua WU
Publication Type:Journal Article
Keywords: Aristolochic acid; aristolchic acid nephropathy; nephrotoxicity; research progress
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(5):1095-1099
CountryChina
Language:Chinese
Abstract: This paper was aimed to discuss the mechanism of aristolchic acid toxicity, pathogenesis and possible causes of aristolchic acid nephropathy. Recent published studies both at home and abroad were summarized on the impact of aristolchic acid on the incidence and progression of aristolchic acid nephropathy. The results showed that traditional Chinese medicine (TCM) containing aristolchic acid was closely associated with the incidence of aristolchic acid nephropathy. It was concluded that the paper provided some suggestions on preventing aristolchic acid nephropathy.