Effect of elemene on patients with advanced liver cancer of leptin, AFP and liver function
- VernacularTitle:榄香烯对晚期肝癌患者血清瘦素、甲胎蛋白及肝功能的影响研究
- Author:
Tiangang LAN
;
Chan CHEN
- Publication Type:Journal Article
- Keywords:
elemene;
hepatocellular carcinoma;
leptin;
AFP;
tumor marker;
liver function
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(8):116-118
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of elemene on leptin, AFP and liver function of patients with advanced liver cancer.Methods 73 cases with advanced liver cancer of our hospital were selected and according to the random number table method were randomly assigned for two groups:control group (37 cases) were given routine clinical therapy;experimental group (36 cases) were treated on the basis of the control group with elemene injection.leptin, AFP ,CRP and liver function were compared after the treatment.ResuIts Compared with control group post-treatment, the leptin level in the experimental group was higher, CRP was lower(P<0.05); the serum level of AFP, CEA and CA199 were lower (P<0.05), the ALT, TBIL, AST, PT were lower ( P<0.05 ) , and the total effective rate was significantly higher ( P<0.05 ) .ConcIusion Elemene injection can improve liver function, elevate serum leptin level, reduce the levels of CRP, tumor marker levels and improve the quality of life .
