Clinical analysis of continuous blood filtration combined with naloxone in treatment of PICU multiple organ dysfunction syndrome
- VernacularTitle:连续性血液滤过联合纳洛酮治疗PICU多器官功能障碍综合征的临床分析
- Author:
Fang YANG
;
Bo ZHAI
;
Zhipeng JIN
- Publication Type:Journal Article
- Keywords:
continuous blood filtration;
naloxone;
multiple organ dysfunction syndrome
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(8):125-127
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate clinical effect of patients with PICU multiple organ dysfunction by continuous blood filtration combined with naloxone.Methods 42 patients with multiple organ function failure were selected and randomly divided into 2 groups.The control group were treated by PICU conventional therapy, the experiment group were treated by continuous blood filtration combined with Naloxone.Vital signs, creatinine, creatine kinase and aspartate aminotransferase levels, length of stay and blood filtration were compared after 1 day and 3 days treatment.ResuIts Compared with control group,heart rate, oxidation index,creatinine and aspartate aminotransferase levels of the experiment group were lower(P<0.05).After 1 day and 3 days, compared with cnontrol group, length of stay and blood filtration of the experiment were lower(P<0.05).ConcIusion Continuous blood filtration combined with naloxone in treatment of multiple organ dysfunction syndrome PICU is effective and reliable.It can significantly improve renal function, shorten the length of hospital stay, and remove inflammatory mediators in plasma of patients.
