The Risk Factor Analysis of Ischemic Stroke Prevalence in Elder Patients With Non-valvular Atrial Fibrillation
10.3969/j.issn.1000-3614.2015.08.009
- VernacularTitle:老年非瓣膜性心房颤动患者发生缺血性脑卒中的危险因素分析
- Author:
Jiangang WANG
;
Jiantang XI
;
Jinsong LI
;
Yajing LIU
- Publication Type:Journal Article
- Keywords:
Elder;
Non-valvular atrial ifbrillation;
Ischemic stroke
- From:
Chinese Circulation Journal
2015;(8):753-756
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the risk factors of ischemic stroke prevalence in elder patients with non-valvular atrial ifbrillation (AF).
Methods: A total of 180 AF patients treated in our hospital from 2010-01 to 2014-12 were retrospectively studied. The diagnosis of ischemic stroke was conifrmed by CT/MRI, and the patients were divided into 2 groups: AF with ischemic stroke group,n=120 and AF alone group,n=60. The CHA2DS2-VASc score, CHADS2 score, plasma levels of homocysteine (HCY), ifbrinogen (FIB), left atrial diameter (LAD), blood lipid proifle and renal function were examined and compared between 2 groups.
Results: There were signiifcant differences on CHA2DS2-VASc score, CHADS2 score, HCY, FIB and LAD between AF with ischemic stroke group and AF alone group,P<0.05. Logistic regression analysis showed that CHA2DS2-VASc score, CHADS2 score, HCY, FIB and LAD were the independent risk factors for ischemic stroke occurrence in non-valvular AF patients. CHA2DS2-VASc score was different from CHADS2 score for stroke stritiifcation.
Conclusion: The CHA2DS2-VASc score and CHADS2 score system combining with plasma levels of HCY, FIB and LAD have the important clinical predictive value for the occurrence of ischemic stroke in elder patients with AF. CHA2DS2-VASc score is more appropriate for screening the low-risk patients, and CHADS2 score is rather appropriate for screening the high-risk patients.
