Analysis of Allergic Adverse Reaction Caused by Non-ionic Iodinated Contrast Media in 52 Patients With Coronary Angiography
10.3969/j.issn.1000-3614.2015.08.006
- VernacularTitle:52例冠状动脉造影患者非离子型含碘对比剂过敏不良反应分析
- Author:
Xu YANG
;
Xiaoqing HUANG
;
Lu HUA
;
Hui SUN
;
Haihua ZHANG
;
Linping WANG
;
Wei ZHANG
;
Li WANG
;
Huimin PANG
;
Yun ZHANG
;
Aimin DANG
- Publication Type:Journal Article
- Keywords:
Non-ionic iodinated contrast media;
Allergic adverse reaction
- From:
Chinese Circulation Journal
2015;(8):741-743
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the current status of allergic adverse reactions caused by non-ionic iodinated contrast media in patients with coronary angiography (CAG).
Methods: A total of 1 225 patients who received non-ionic iodinated contrast media for CAG in our hospital from 2011-02 to 2013-09 were retrospectively studied. There were 52 patients suffered from allergic adverse reactions including 47 (90.38%) male and 5 (9.62%) female. The allergic reaction to iodixanol, iohexol, iopamidol and iopromide were in 34, 3, 3 and 12 patients respectively. The clinical symptoms and outcomes of allergic reaction in 4 iodinated contrast media were analyzed.
Results: There were 40/52 (76.92%) patients with mild allergic reaction, 11(21.15%) with moderate and 1 (1.92%) with severe reaction. 13 patients had the reaction within 1 hour of contrast media injection and 39 had the reaction between 1 hour to 3 days of contrast media injection. There 34 patients were cured by symptomatic and anti-allergic treatment, 1 patient was rescued from allergic shock and no death occurred.
Conclusion: Application of non-ionic iodinated contrast media in CAG is safe, while closely observe the allergic adverse reaction with the in time and symptomatic treatment is very important in clinical practice.
