Study on changes of IL-6, IL-10 and TNF-αafter cholecystectomy
- VernacularTitle:胆囊摘除术后患者白介素6、白介素10以及TNF－α水平变化研究
- Author:
Xianyi ZHANG
;
Hua YANG
;
Shenglin LONG
;
Hao LIN
;
Yingqiang CHEN
- Publication Type:Journal Article
- Keywords:
laparoscopic cholecystectomy;
IL-6;
IL-10;
TNF-α
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(8):89-91
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of IL-6, IL-10 and TNF-αafter cholecystectomy.Methods 46 cases with cholecystolithiasis were selected and divided into 2 groups.23 in control group were treated with open cholecystectomy, experimental group were treated with laparoscopic cholecystectomy.The levels of IL-6, TNF-α, IL-10 and CD4 +/CD8 +T were compared in the two groups pre-and post-treatment.ResuIts Compared with pre-treatment, two groups of patients with IL-10, TNF-α, IL-6 and CD4 +T and CD4 +/CD8 +T increased (P<0.05), compared with control group, experimental group IL-10, TNF-α, IL-6, CD4 +/CD8 +T levels were higher (P<0.05).ConcIusion Laparoscopic cholecystectomy can significantly reduce the IL-6, TNF-αand IL-10 levels, reduce the body′s stress response to surgery, and reduce blood flow, shorten the operation time.
