Progress in the study of dawn penomenon and extended dawn phenomenon in patients with diabetes

VernacularTitle:糖尿病黎明现象及延伸黎明现象的研究进展
Author: Hang SU ; Jian ZHOU ; Weiping JIA
Publication Type:Journal Article
Keywords: Dawn phenomenon; Extended dawn phenomenon; Continuous glucose monitoring
From: Chinese Journal of Endocrinology and Metabolism 2015;(8):739-742
CountryChina
Language:Chinese
Abstract: [Summary] Thedawn phenomenon is a term used to describe hyperglycemia or an increase in the amount of insulin needed to maintain normoglycemia, occurring in the absence of antecedent hypoglycemia, during the early morning hours, and mostly affecting children with type 1 diabetes. Currently, hyperglycemia before breakfast time is defined as dawn phenomenon, and postbreakfast abnormal hyperglycemia is referred as the extended dawn phenomenon. Dawn phenomenon is regarded as the result of the β cell dysfunction, which increased endogenous glucose production and the persistent insulin resistance. By using continuous glucose monitoring technology, dawn phenomenon can be effectively identified:The difference between the lowest glucose level during nocturnal time and the glucose value before breakfast over 1. 11 mmol/L. And the long-acting insulin analogs and insulin pump are effective treatments for dawn phenomenon.