The role of diffusion-weighted imaging for breast MRI
10.3969/j.issn.1007-3969.2015.08.007
- VernacularTitle:乳腺弥散加权成像在乳腺疾病中的作用
- Author:
Qinghua MIN
;
Jun YANG
;
Kangwei SHAO
;
Caisong ZHU
;
Lixin YUAN
;
Huiling XU
;
Peng LI
;
Wenjie LU
- Publication Type:Journal Article
- Keywords:
Diffusion-weighted imaging;
Dynamic contrast-enhanced;
Magnetic resonance imaging;
Breast cancer
- From:China Oncology
2015;(8):602-607
- CountryChina
- Language:Chinese
-
Abstract:
Background and purpose:Diffusion-weighted imaging (DWI) is a non-invasive technique of breast magnetic resonance imaging (MRI). DWI is an alternative to dynamic contrast-enhanced (DCE) MRI for differentiating malignant from benign lesions in breast screening or not. This study aimed to evaluate the potential role of DWI in differentiating malignant breast lesions from benign lesions.Methods:Seventy-four patients underwent digital mammography, DCE and DWI (49 patients’b-value of 0, 400, 600 and 800 s/mm2). The detectability, sensitivity and speciifcity of DWI and DCE were compared. Absolute apparent diffusion coefifcient (ADC) was compared with standardized ADC for quantitative analysis.Results:Sixty-four of 74 patients had positive pathologic findings (38 malignant, 26 benign). All of the malignant lesions were detected on DWI and DCE. The sensitivity of DWI was 83.33%, 90.00% and 93.33%, and the specificity was 85.91%, 76.19% and 72.72%, forb-value of 400, 600 and 800 s/mm2, respectively. The sensitivity and speciifcity of DCE were 86.61% and 90.48%. There was no signiifcant difference between absolute and standardized ADC in detecting breast cancer (P>0.05).Conclusion:DWI is an important complemented technique to DCE-MRI for differentiating malignant from benign lesions in breast MRI.
