Molecular and genetic diagnosis of male infertility：practices and challenges
10.3760/cma.j.issn.1009-9158.2015.08.003
- VernacularTitle:男性不育的分子和遗传诊断的现状与挑战
- Author:
Zheng LIU
;
Xiliang WANG
;
Guangbin QIU
- Publication Type:Journal Article
- Keywords:
Infertility,male;
Molecular diagnostic techniques;
Chromosome deletion;
Genetic techniques
- From:
Chinese Journal of Laboratory Medicine
2015;(8):511-513
- CountryChina
- Language:Chinese
-
Abstract:
Genetic factors are important causes of male infertility and account for about 30%infertility cases.Therefore, it is necessary to carry out molecular and genetic detections in the diagnosis and treatment of male infertility.Here the most commonly used techniques for molecular and genetic diagnosis of male infertility in recent years are discussed , including chromosomal abnormities analysis , Y chromosome microdeletions detection , gene mutation screening and sperm quality and function examination.
