Clinical distribution and drug resistance of Pseudomonas aeruginosa in Ningbo during 2010 and 2013
10.3760/cma.j.issn.1674-2397.2015.04.007
- VernacularTitle:2010至2013年宁波地区铜绿假单胞菌的临床分布及耐药性分析
- Author:
Shifang SUN
;
Xingbei WENG
;
Chaofen LI
;
Zaichun DENG
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
Clinical distribution;
Drug resistance;
Carbapenems
- From:
Chinese Journal of Clinical Infectious Diseases
2015;(4):317-321
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical distribution and drug resistance of Pseudomonas aeruginosa in Ningbo area .Methods Pseudomonas aeruginosa strains isolated from the Affiliated Hospital of Ningbo University School of Medicine , Ningbo First Hospital , and Ningbo Ninth Hospital during January 2010 and December 2013 were collected .The clinical distribution of the strains was analyzed , and the antimicrobial susceptibility was determined with Kirby-Bauer method.WHONET 5.6 software was used for data analysis.Results A total of 1 757 Pseudomonas aeruginosa strains were collected in 4 years, accounts for 6.6% (1 757/26 544) of total bacterial strains isolated.Among 1 757 strains, 622 (35.4%) were isolated from intensive care unit ( ICU), and 322 (18.3%) from respiratory department.Most strains (1 045/1 757, 59.5%) were isolated from sputum specimens , followed by urine and succus prostaticus (148/1 757, 8.4%), bronchoalveolar lavage fluid (116/1 757, 6.6%), pus and wound secretion (237/1 757, 4.6%) .Strains were highly resistant to most commonly used antibiotics , and the resistance remained steady during four years.While the positive rates of carbapenem-resistant Pseudomonas aeruginosa (CRPA) were increased, which were 35.8%,45.8%,44.5% and 54.3% in each year.Conclusion Pseudomonas aeruginosa presents a wide clinical distribution and high resistance to multiple antibiotics in Ningbo area .
