The prognostic value of CRP,PCT and IL-6 in liver cirrhosis with systemic inflammatory response syndrome
10.3969/j.issn.1671-8348.2015.22.009
- VernacularTitle:CRP、PCT、IL-6对评价肝硬化伴全身炎性反应综合征预后的意义
- Author:
Wei ZHAO
;
Zhijun QU
;
Guohang LI
;
Guilong ZHUANG
- Publication Type:Journal Article
- Keywords:
liver cirrhosis;
C-reactive protein;
calcitonin;
interleukin-6;
systemic inflammatory response syndrome
- From:
Chongqing Medicine
2015;(22):3050-3052
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the serum levels of C-reactive protein (CRP),procalcitonin (PCT),and interleukin-6(IL-6) and evaluate their prognostic values in liver cirrhosis with systemic inflammatory response syndrome(SIRS).Methods A total of 56 patients with liver cirrhosis and systemic inflammatory response syndrome were divided into two groups,improved group(n =39)and death group(n=1 7).Serum CRP、PCT、IL-6 levels were measured at the first day,third day and seventh day after SIRS. Results CRP,PCT and IL-6 levels of two groups were no statistically significant difference in the first day (P >0.05).PCT and IL-6 levels of two groups were no statistically significant difference in the third day (P >0.05).CRP levels in improved group were lower than those in death group in the third day (P <0.05).CRP,PCT and IL-6 levels in improved group were lower than those in death group in the seventh day (P <0.05).There was no statistically significant difference of CRP,PCT and IL-6 at the first day, third day and seventh day in death group (P >0.05).CRP levels at the third day and seventh day were lower than those at the first day in improved group (P <0.05).PCT and IL-6 levels at the seventh day were lower than those at the first day in improved group (P <0.05).Conclusion Poor prognosis was showed at sustained high levels of CRP,PCT and IL-6.Compared with PCT and IL-6, CRP might be more rapid in showing condition improved.
