The progression on the research of haem oxygenase-1 and diabetic peripheral neuropathy
10.3969/j.issn.1006-6187.2015.07.019
- VernacularTitle:血红素加氧酶-1与糖尿病周围神经病变的研究进展
- Author:
Qunli WU
;
Xiaochun LIANG
- Publication Type:Journal Article
- Keywords:
Diabetic peripheral neuropathy (DPN );
Oxidative stress (OS );
Inflammation;
Haem oxygenase-1(HO-1)
- From:
Chinese Journal of Diabetes
2015;(7):653-656
- CountryChina
- Language:Chinese
-
Abstract:
[Summary] The pathogenesis of diabetic peripheral neuropathy (DPN ) is the result of complex multiple concurrent pathogenic factors ,among which oxidative stress and inflammation play important roles. Multiple data have indicated that haem oxygenase‐1 (HO‐1) and its degradation products products possess the functions of anti‐oxidation ,anti‐inflammation ,anti‐apoptosis and pro‐angiogenesis ,which now becomes a new target for the treatment of DPN. We will briefly review the progression on the research of HO‐1 and DPN.
