Influence of blood glucose level at hospitalization on no-reflow and prognosis in non-diobetic patients with myocardial infarction after emergency coronary intervention
10.3969/j.issn.1008-0074.2015.04.09
- VernacularTitle:血糖水平对非糖尿病心梗患者 PCI 后无复流及预后的影响
- Author:
Yajing WEI
;
Junlong HOU
;
Ali WANG
;
Jianhui CHEN
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Angioplasty,balloon,coronary;
No-reflow phenomenon
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2015;24(4):379-382
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the influence of different blood glucose level at hospitalization on no-reflow and prognosis in patients with acute myocardial infarction (AMI),but without diabetes after emergency percutaneous coronary intervention (PCI).Methods:A total of 678 non-diabetic AMI patients undergoing PCI were selected.Ac-cording to blood glucose level at hospitalization,patients were divided into normal group (n=312),blood glucose level higher group (higher group ,n=201)and blood glucose level extremely high group (extremely high group,n=165).Clinical characteristics,no-reflow after PCI and incidence of cardiovascular events within 30d after PCI were compared among three groups.Results:Compared with normal group and higher group,there were significant rise in age,percentages of >1 location of myocardial infarction and Killip's ≥ class II,white blood cell count instant af-ter hospitalization,peak value of creatine kinase (CK)and CK-isoenzyme (CK-MB)in extremely high group,P <0.01 all;Compared with normal group,the age,peak value of CK and CK-MB significantly rose in higher group (P<0.01 all).Along with blood glucose rose,incidence rate of no-reflow significantly increased (17.0% vs.38.8%vs.49.7%),left ventricular ejection fraction (LVEF)on 30d after PCI gradually reduced [(68.6± 5.7)% vs. (62.2±6.4)% vs.(55.6±6.9)%]in above-mentioned 3 groups in turn,there was significant difference between any two groups,P <0.05 or <0.01.Conclusion:Stress hyperglycemia possesses great influence on no-reflow and prognosis in non-diabetic AMI patients after PCI.
