Relationship between serum cystatin C level and coronary artery lesion after off-pump coronary artery bypass grafting
10.3969/j.issn.1008-0074.2015.04.10
- VernacularTitle:不停跳冠脉旁路分流术后血清胱抑素C水平与冠脉病变的关系
- Author:
Zifan ZHOU
;
Juyi WAN
;
Wenbin LI
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Cystatin C;
Coronary artery bypass,off-pump
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2015;24(4):382-385
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe serum cystatin C (Cys C)level in patients before and after off-pump coronary ar-tery bypass grafting (OPCABG),and explore its relationship with coronary artery lesion.Methods:A total of 321 patients,who received OPCABG in department of heart surgery of our hospital from Aug 2013 to Nov 2013,were selected.According to number of diseased coronary vessels,they were divided into single-vessel group (n= 11), double-vessel group (n=33)and multi-vessel group (n=277).Double antibody enzyme linked immunosorbent assay (ELISA)was used to measure serum Cys C level in all groups.Results:The Cys C levels in single-vessel group, double-vessel group,multi-vessel group before OPCABG were (0.732 ± 0.286)mg/L, (0.807 ± 0.265)mg/L, (0.911±0.273)mg/L respectively,there were significant difference (F=3.942,P =0.038);and after OPCABG were (0.616±0.198)mg/L,(0.607±0.201)mg/L, (0.646±0.166)mg/L respectively ,there were no signifi-cant difference (F=0.493,P =0.617),namely there was no significant relationship between coronary artery disease extent and Cys C level after OPCABG,P >0.05. Conclusion:There is no significant relationship between original coronary artery disease extent and serum cystatin C level after off-pump coronary artery bypass grafting,namely off-pump coronary artery bypass grafting is an effective therapeutic measure for patients with coronary heart disease.
