Relationship between early intervention treatment and long-term prognosis in patients with acute non-ST segment elevation myocardial infarction
10.3969/j.issn.1008-0074.2015.04.25
- VernacularTitle:早期介入治疗与 NSTEMI 患者长期预后的关系
- Author:
Zhi QIANG
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Angioplasty,balloon,coronary;
Prognosis
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2015;24(4):434-438
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze relationship between early intervention treatment and long-term prognosis in pa-tients with acute non-ST segment elevation myocardial infarction (NSTEMI).Methods:A total of 948 acute NSTE-MI patients were enrolled.According to NSTEMI intervention treatment timing,they were divided into early inter-vention group (received intervention treatment within 48h n=411,)and late intervention group (received interven-tion treatment after48h,n=537).According to TIMI risk score,the two groups were further divided into low risk subgroup,medium risk subgroup and high risk subgroup,the clinic long-term outcome was compared among all groups.Results:Compared with late intervention group,during one year follow-up,there were significant reduction in mortality during hospitalization (4.8% vs.2.2%)and incidence rate of major adverse cardiovascular events (MACE,13.4% vs.10.0%)in early intervention group,P <0.01 both;in early intervention group,mortality dur-ing hospitalization of low and medium risk patients was significantly lower than that of high risk patients (3.3% vs. 8.9%,P <0.01).Multi-factor regression analysis indicated that aged,high Killip class,reduced left ventricular e-jection fraction,high TIMI risk score and late intervention treatment were independent risk factors for clinic long-term outcome in NSTEMI patients (OR=1.027~2.079,P <0.05 or <0.01).Conclusion:Early intervention treat-ment can improve prognosis in NSTEMI patients.
