The clinical value of serum cystatin C in kidney assement of lung cancer
10.3969/j.issn.1673-4130.2015.16.031
- VernacularTitle:血清胱抑素C在肺癌患者肾脏功能评估中的应用价值
- Author:
Xiangyu DING
;
Xiuli GOU
;
Jie ZHANG
;
Guangli SHI
- Publication Type:Journal Article
- Keywords:
cystatin C;
lung cancer;
kidney assement
- From:
International Journal of Laboratory Medicine
2015;(16):2363-2364
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the serum levels of cystatin C (CysC)in lung cancer and its clinical significances for kidney assement.Methods The serum of 120 patients with lung cancer and 50 healthy controls were collected.All the patients were en-rolled in Beijing Chest Hospital,Capital Medical University,from June 2012 to October 2013.Full-automatic biochemistry analyzer was used to examine the levels of serum CysC.Results The level of serum CysC in patients with lung cancer was significantly higher than that of healthy controls(t = 4.771,P < 0.05 ).The sensitivity of CysC(81.7%)was significantly higher than that of BUN(66.7%)and Cr(45%)(χ2 =25.326,P <0.05),and there were no significantly difference of the specificity among them(χ2 =3.468,P >0.05).Conclusion Serum CysC was a useful biochemistry marker for kidney assement in lung cancer,and have better clinical significances than BUN and Cr.
