Correlation and significance of combined detection of D-Dimer,cTnI and NT-ProBNP in acute coronary syndrome
10.3969/j.issn.1673-4130.2015.16.036
- VernacularTitle:急性冠状动脉综合征患者 D-二聚体、cTnI 和 NT-ProBNP联合检测的意义及相关性分析
- Author:
Di HUANG
;
Tao LI
;
Chenyu SHANG
;
Yan MA
;
Xiaobin WU
;
Haibiao LIN
;
Yunlong GAO
;
Peifeng KE
- Publication Type:Journal Article
- Keywords:
acute coronary syndrome;
D-Dimer;
cardic troponin I;
N-terminal probrain natriuretic peptide
- From:
International Journal of Laboratory Medicine
2015;(16):2375-2377
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the significance of combined detection of D-Dimer,cardic troponin I(cTnI)and N-terminal pro-brain natriuretic peptide(NT-ProBNP)in acute coronary syndrome and the correlation between them.Methods 143 patients with acute coronary syndrome were selected as the observation group,and 40 CAG negative people as the control group.The difference between the two groups was compared and the correlation was analyzed.According to different diagnostics,patients in the observa-tion group were separated into 3 groups,unstable angina pectoris,non ST segment elevation myocardial infarction and ST segment elevation myocardial infarction.The correlation of D-Dimer,cTnI and NT-ProBNP with the severity of coronary artery disease was analyzed.Results The levels of D-Dimer,cTnI and NT-ProBNP in the observation group were higher than those in the control group,and the difference was statistically significant(P < 0.05 ).The severity of coronary artery disease had positive correlation with the test results (P <0.05).Conclusion The combined detection of D-Dimer,cTnI and NT-ProBNP could help to diagnose the acute coronary syndrome and the test result has a positive correlation with the severity of acute coronary syndrome.
