Clinical observation on the application of terbinafine and mizolastine in combined treatment of chronic ec-zema with dermatophytes infection
10.16571/j.cnki.1008-8199.2015.08.011
- VernacularTitle:特比萘芬联合咪唑斯汀治疗伴有皮肤癣菌感染的慢性湿疹的疗效分析
- Author:
Fang LIU
;
Wenxing HU
;
Haibo LIU
;
Qingtao KONG
;
Meihua ZENG
;
Jun CHEN
;
Dequan DENG
;
Hong SANG
- Publication Type:Journal Article
- Keywords:
Anti-fungal therapy;
Chronic Eczema;
Derma-tophytosis
- From:
Journal of Medical Postgraduates
2015;(8):832-835
- CountryChina
- Language:Chinese
-
Abstract:
Objective The article was to observe the clinical efficacy of the application of terbinafine and mizolastine in com -bined treatment of chronic eczema ( CE) with dermatophytes infection , so as to define the etiology role of dermatophytes in allergic dis-eases. Methods All subjects were randomly divided into experiment group and control group .The experiment group was treated with the combination of terbinafine and mizolastine , while the control group took mizolastine orally alone .EASI grading , recovery rate and effective rate were evaluated at 2, 3 week after the treatment and EASI grading and recurrence rate were evaluated at 4 weeks after the treatment. Results 79 patients had finished the experiment .Significant difference was found in the effective rates between two groups at 3 weeks after treatment (P<0.05).At 4 weeks after the treatment, EASI value and recurrence rate in experiment group were obviously lower than those in control group (P<0.05). Conclusion Good therapeutic effect has been achieved through the ap-plication of terbinafine and mizolastine in combined treatment of CE with dermatophytes infection , which implies dermatophytes plays an important role in the etiology of CE .
