Diagnostic Value of 4 μg/mL vancomycin screening plate for vancomycin-non-susceptible Staphylococcus aureus:a Meta-analysis
10.3969/j.issn.1673-4130.2015.16.013
- VernacularTitle:4μg/mL 万古霉素琼脂平板对万古霉素不敏感葡萄球菌筛查价值的 Meta 分析
- Author:
Shumei CAI
;
Yabin ZHANG
- Publication Type:Journal Article
- Keywords:
vancomycin screening plate;
vancomycin-non-susceptible Staphylococcus aureus;
population analysis profiles-ar-ea under the curve;
Meta-analysis
- From:
International Journal of Laboratory Medicine
2015;(16):2321-2323
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic accuracy of 4 μg/mL vancomycin screening plate (4VA)for vancomycin-non-susceptible Staphylococcus aureus.Methods The diagnosis trials on 4VA for vancomycin-non-susceptible Staphylococcus aureus were searched in the databases such as PubMed(1 966 to Aug.2013),The Cochrane Library(the second phase of 2013),ISI Web of Knowledge(1 980 to Aug.2013),CNKI (1 964 to Aug.2013),VIP (1 989 to Aug.2013)and Wanfang(1 998 to Aug.2013),mean-while the manual.Two reviewers evaluated the quality of the included trials according to the quality assessment of diagnostic accu-racy studies,and then meta-analysis was performed using Meta-Disc 1.4 software.Results A total of 3 trials involving 974 partici-pants were included.The results of meta-analysis showed that the weighted sensitivity,specificity,positive likelihood ratio,negative likelihood ratio and diagnostic odds ratio,were 0.805 [95%CI (0.047 to 0.563)],0.921 [95%CI (0.901 to 0.938)],10.804 [95%CI (5.5 1 1 to 21.181)],0.1 62 [95%CI (0.71 to 1.0)]and 69.721 [95%CI (1 1.740 to 414.06)]respectively.Conclusion 4VA for vancomycin-non-susceptible Staphylococcus aureus has a very high specificity and sensitivity,so 4VA could be used to creening plate (4VA)for vancomycin-non-susceptible Staphylococcus aureus in clinic.
