Observation of Curative Effect ofHongteng Chang'an Decoction in Treating Ulcerative Colitis
10.3969/j.issn.1005-5304.2015.09.007
- VernacularTitle:红藤肠安汤治疗溃疡性结肠炎疗效观察
- Author:
Yun ZHOU
;
Ji SUN
;
Yaying WU
;
Hongwei WANG
;
Jing KONG
;
Jin TANG
- Publication Type:Journal Article
- Keywords:
ulcerative colitis;
Hongteng Chang'an Decoction;
ESR;
CRP;
Baron score
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2015;(9):22-25
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy and safety ofHongteng Chang'an Decoction in treating mild and moderate ulcerative colitis (UC) cases.Methods Totally 120 patients of mild or moderate UC were randomly divided into two groups:TCM group of 60 patients, treated by self-madeHongteng Chang'an Decoction;Western medicine group of 60 patients, treated by mesalazine orally. The treatment course of both groups was 6 weeks, also with two-week follow-up. The ESR and CRP levels before and after treatment, the healing of colonic mucosa under endoscopy (according to the Baron score), the clinical efficacy and safety were analyzed statistically.Results CRP of both groups decreased significantly, with obvious statistical significance (P<0.05);ESR of both groups decreased, without statistical significance (P>0.05). The effects of healing of colonic mucosa under endoscopy of TCM group and Western medicine group were 61.37% (27/44) and 64.29% (27/42), respectively, without obvious statistical significance (P>0.05). The total effective rates of TCM group and Western medicine group were 86.7% (52/60) and 75.0% (45/60), respectively, and the TCM group was superior to the Western medicine group (P<0.05).ConclusionHongteng Chang'an Decoction can reduce the serum level of CRP of the mild and moderate UC patients effectively, relieve inflammation, and promote the healing of colonic mucosa. The treatment of mild and moderate ulcerative colitis byHongteng Chang'an Decoction has good clinical efficacy, without toxic side effects.
