The application value of fecal calprotectin in inflammatory bowel disease
10.16571/j.cnki.1008-8199.2015.08.020
- VernacularTitle:粪便钙卫蛋白检测在炎症性肠病中的应用价值
- Author:
Yuanning YE
;
Fangyu WANG
- Publication Type:Journal Article
- Keywords:
Fecal calprotectin;
Inflammatory bowel disease;
Diagnosis;
Prediction
- From:
Journal of Medical Postgraduates
2015;(8):865-869
- CountryChina
- Language:Chinese
-
Abstract:
The diagnosis and monitoring of inflammatory bowel disease mainly depend on clinical presentation , endoscopical , histopathological and imaging findings .It has been demonstrated that fecal inflammatory biomarkers can be potential markers to replace endoscopy diagnosed disease activity .Calprotectin is a binding protein of calcium and zinc , which is mainly derived from neutrophils and macrophages .Calprotectin is an accurate noninvasive biomarker in diagnosing and monitoring inflammatory bowel disease in clin -ics.This paper reviews the progress of fecal calprotectin in the diagnosis, disease activity evaluation, clinical monitoring and prognosis of inflammatory bowel disease .
