Analysis on Variations of Serum Pepsinogen in Different Altitude Population
10.3969/j.issn.1671-7414.2015.03.009
- VernacularTitle:不同海拔高度人群胃蛋白酶原血清水平差异性分析
- Author:
Juan HU
;
Peng XU
;
Yonghe HU
;
Wei LIN
- Publication Type:Journal Article
- Keywords:
pepsinogen;
plateau;
partial pressure of oxygen;
gastrosia
- From:
Journal of Modern Laboratory Medicine
2015;(3):32-34
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the serum pepsinogen (PG)in different altitude population.Methods By testing serum PG of people from different altitudes,detected the concentration of serum PG.Results The serum PGI,serum PGII and PGR were respectively 136.89±22.64 μg/L,10.05 ± 5.14 μg/L and 13.07 ± 7.41 in 1 000 m group,and they were 30.87 ± 48.66 μg/L,11.55±2.78 μg/L and 12.89±4.76 in 1 300 m group.There were significant difference in PGI and PGII(P <0.05)except PGR (P >0.05)between the two groups.The corresponding indices in 1500m group (126.64±29.84 μg/L, 12.18±5.99 μg/L and 12.2±14.84,respectively),the serum PGI was decreased obviously compared with those groups (P<0.05),the serum PGII was increased obviously compared with those groups (P < 0.05),No significant difference was found when compared with those groups (P >0.05).The serum PGI was negative correlated with higher altitudes,the ser-um PGII was positively correlated with higher altitudes.Conclusion The study found that the serum PGI content would re-duce with the increase of altitude,and on the contrary the serum PGII would rise with the increase of altitude.The main rea-son that the serum PG change may be influenced by oxygen partial pressure.
