External Quality Assessment of Hemoglobin A2(HbA2) and Hemoglobin F(HbF)Measurement

VernacularTitle:血红蛋白A2和F的室间质量评价结果分析
Author: Falin HE ; Wei WANG ; Kun ZHONG ; Zhiguo WANG
Publication Type:Journal Article
Keywords: external quality assessment; hemoglobin A2; hemoglobin F; quality control; thalassemia
From: Journal of Modern Laboratory Medicine 2015;(2):156-159
CountryChina
Language:Chinese
Abstract: Objective To evaluate hemoglobin A2 and F (HbA2 and HbF)assays in part of Thalassemia screening laborato-ries in China.Methods Two lots of controls were sent to 50 Thalassemia screening laboratories.Test results of HbA2 and HbF were collected,analyzed and evaluated by different method groups.Results 49 of all laboratories reported the results and the rate of return was 98%.The proportion of laboratories reporting acceptable results for HbA2 and HbF testing was 42.9~92.3% and 27.3% ~ 84.6% respectively.HbA2 test results from 3 laboratories for Lot 201311 and 4 for 201312 were unsatisfactory.And HbF test results from 5 laboratories for Lot 201311 and 3 for 201312 were unsatisfactory.Conclu-sion Conclude that quality in the measurement of HbA2 and HbF should be improved.