Significance of Urinary NT-proBNP Levels for Diagnosis of Chronic Heart Failure
10.3969/j.issn.1671-7414.2015.02.042
- VernacularTitle:尿液 NT-proBNP 水平在慢性心力衰竭诊断中的意义
- Author:
Yan HUA
;
Haijiang WANG
- Publication Type:Journal Article
- Keywords:
urine;
NT-proBNP;
chronic heart failure
- From:
Journal of Modern Laboratory Medicine
2015;(2):134-136
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of the levels of urinary NT-proBNP whether is similar with the levels of blood NT-proBNP for the diagnosis of chronic heart failure.Methods 79 patients with chronic heart failure (NYHA Ⅰ~Ⅳ)as a research group,and 53 healthy people as a control group,the levels of urinary and blood NT-proBNP on two groups were measured respectively by Roche cobas h 232 cardiac markers detector and compared the difference of the levels of urinary NT-proBNP and blood NT-proBNP between the two groups.Results The levels of urinary and blood NT-proBNP in pa-tients with chronic heart failure were much higher than those in healthy subjects,respectively (P <0.01).The concentration of urinary NT-proBNP increased gradually with more severe symptoms.The level of urinary NT-proBNP was positively cor-related with the levels of blood NT-proBNP.Conclusion The levels of urinary NT-proBNP is a new candidate marker for the diagnosis of chronic heart failures and it provides a similar accuracy with the levels of blood.
