Diagnosis Value of Joint Detection of Critical Patients Procalcitonin and (1,3)-beta-D Glucan with Deep Fungus Infection in ICU
10.3969/j.issn.1671-7414.2015.02.037
- VernacularTitle:ICU 危重病患者深部真菌感染血清中降钙素原和（1，3）-β-D 葡聚糖联合检测的临床意义
- Author:
Yan WEN
;
Aisheng LIU
;
Yong ZHANG
;
Wei LI
- Publication Type:Journal Article
- Keywords:
procalcitonin;
(1,3)-beta-D glucan;
ICU;
incidence of deep fungal infection;
value
- From:
Journal of Modern Laboratory Medicine
2015;(2):120-122
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical application of jiont detection of critical patients procalcitomin (PCT)and (1,3)-beta D-glucan with deep fungus infection in ICU.Methods From November 2012 to August 2014 diagnosed with deep fun-gal infection of ICU critical patients,106 cases of patients with serum PCT and (1,3)-beta-D glucan content detection,and ICU of deep fungal infection in critically ill patients,519 cases were analyzed,with differencesbetween the paired t test to compare the results.Results 106 patients with deep fungal infection of ICU critical patients serum PCT for 0.701 ±0.22 pg/ml and (1,3)-beta-D glucan for 37.82±18.43 pg/ml,significantly higher than the 519 cases of ICU of deep fungal infec-tion in critically ill patients in the serum PCT for 0.238±0.12 pg/ml and (1,3)-beta-D glucan for 14.96 ±4.37 pg/ml, comparing differences between both results was statistically significant (t=7.426,8.179,P <0.05).106 patients with deep fungal infection of ICU critical patients serum PCT positive detection rate was 57.5% (61/106),significantly lower than the (1,3)-beta-D glucan positive detection rate 89.6% (95/106),difference was statistically significant (χ2 = 13.645,P <0.05).Conclusion Deep fungal infection in critical care patients in the ICU in the serum PCT and (1,3)-beta-D glucan con-tent of deep fungus infection in critically ill patients was significantly higher than the ICU,PCT and (1,3)-beta-D glucan joint detection of deep fungal infection in patients with ICU critical patients diagnosis has important clinical significance.
