Comparison of Two Kits in Determining Anti-Cardiolipin

VernacularTitle:两种试剂检测抗心磷脂抗体的比较
Author: Yijia ZHU ; Longzhen XU ; Wei HU ; Yue TAO ; Kui ZHANG ; Qingfei WANG
Publication Type:Journal Article
Keywords: anti-cardiolipin; anti-β2-glycoprotein I antibody; association
From: Journal of Modern Laboratory Medicine 2015;(2):94-96
CountryChina
Language:Chinese
Abstract: Objective To compare the results of anti-cardiolipin (ACA)measuring by two commercial available kits.Methods ACA in total of 66 serum samples were both determined by kits from Euroimmun and YHLO simultaneously,then the re-sults were analyzed comparatively and correlatively.The Euroimmun kit was applied to determination the level of ACA-IgA/G/M,and the YHLO kit determined ACA-IgG/M and anti-β2-glycoprotein I antibody (β2GPI IgG).Results The positive rate by Euroimmun kit was 37.88% (25/66),while 31.82% (21/66)was positive (one positive among ACA-IgG,IgM andβ2GPI IgG)when determined by YHLO kit,and there was no significant difference between the two kits.The accordance rate of the two kits was 87.88% (58/66).The ACA-IgA/G/M value by Euroimmun kit and the summation of ACA-IgG, IgM andβ2GPI IgG by YHLO kit showed well linear correlation (r 2 =0.892,P <0.01).Conclusion Results from the two kits were consistent and correlated well,and they are suitable for the clinical application;these two kits have their own char-acteristics,which could be used by individual or combination accordingly.