Comparatively Study on the Thromboelastography and Light Transmission Aggregometry in Monitoring Clopidogrel Effect
10.3969/j.issn.1671-7414.2014.06.036
- VernacularTitle:血栓弹力图法与光学比浊法监测氯吡格雷疗效的对比研究
- Author:
Yuan HUANG
;
Wei ZHANG
;
Qianlin YANG
;
Ting ZHANG
;
Zhihua XIE
- Publication Type:Journal Article
- Keywords:
acute coronary syndrome;
clopidogrel;
light transmission aggregometry;
thromboelastography
- From:
Journal of Modern Laboratory Medicine
2014;(6):113-115
- CountryChina
- Language:Chinese
-
Abstract:
Objective To comparatively study the difference between thromboelastography (TEG)and light transmission ag-gregometry (LTA)in monitoring clopidogrel effect in patients with acute coronary syndrome.Methods 68 patients with a-cute coronary syndrome,who were in hospital from February to December 2013,were enrolled in this study.They received TEG and LTA to determine platelet aggregation.Results Clopidogrel effect was (47.84±26.04)% and (45.64±20.92)%respectively by TEG and LTA.There were negative correlation between LTAADP and TEGADP(r=-0.752,P<0.001),pos-itive correlation between LTAADP and MAADP(r=0.789,P<0.001),negative correlation between TEGADP and MAADP(r=-0.820,P<0.001).Conclusion There was a good correlation between the two methods.TEG can be used to evaluate thera-peutic effect of Clopidogrel effect.
