Frequency of the Occurrence of Genes ErmA,ErmB,ErmC and MsrA Among Staphylococcus Aureus Strains
10.3969/j.issn.1671-7414.2014.06.022
- VernacularTitle:金黄色葡萄球菌临床分离株ermA，ermB，ermC和msrA基因检测分析
- Author:
Qing WU
;
Wanzhou XU
;
Yan LI
- Publication Type:Journal Article
- Keywords:
Staphylococcus aureus;
erythromycin;
clindamycin;
resistance gene
- From:
Journal of Modern Laboratory Medicine
2014;(6):69-71
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the resistant characteristics of staphylococcusaureus and the relationship between eryth-romycin,clindamycin resistance phenotypes and its resistance mechanism.Methods 7 6 Saphylococcus aureus isolated from clinical specimens was identified and antimicrobial susceptibility tested by BD all-automatic microbiology analysis system.U-sing the D-test method to analyzed Erythromycin induced by clindamycin resistance.Genes (ermA,ermB,ermC and msrA) were detected by PCR methods.Results In 76 staphylococcus aureus straims gene ermA,ermB and ermC was found in 29 strains.The msrA gene was present in the 2 strains.The coincidence rate of ermA,ermB,ermC and msrA gene detection with erythromycin was 82.9%.The coincidence rate of ermA,ermB,ermC and msrA gene detection with chindamycin was 89.5%.Conclusion Clindamycin and erythromycin resistance of Staphylococcusaureus is related to the encoding of gene er-mA,ermB,ermC and msrA.
