An Immunochromatographic Lateral-flow Device(LFD) for Rapid Diagnosis of Aspergillosis
10.3969/j.issn.1671-7414.2014.06.003
- VernacularTitle:一种用于曲霉病快速诊断的免疫层析侧流装置(LFD)
- Author:
Guoyong ZHANG
;
Fangqiu LI
- Publication Type:Journal Article
- Keywords:
invasive aspergillosis;
extracellular glycoprotein;
rapid diagnosis
- From:
Journal of Modern Laboratory Medicine
2014;(6):9-11
- CountryChina
- Language:Chinese
-
Abstract:
An immunochromatographic Lateral-Flow Device (LFD)was invented for rapid serodiagnosis of Invasive Asper-gillosis by foreign investigator.A monoclonal antibody against Aspergillus extracellular glycoprotein is used as capture anti-body and detection antibody in LFD.LFD is a simple,rapid,single sample performance technique by which Aspergillus ex-tracellular glycoprotein in serum and/or bronchoalveolar lavage fluid (BAL)of patients can be detected.The principle of LFD and the features of antigen and antibody involved in the technique will be described.The diagnositic value of novel LED is compared with that of GM test and PCR.