Changes of PaO2 and PaCO2 in patients with chronic obstructive pulmonary disease
- Author:
Hung Ba Nguyen
- Publication Type:Journal Article
- Keywords:
chronic obstructive pulmonary disease
- MeSH:
Pulmonary Disease, Chronic Obstructive;
Gases
- From:Journal of Practical Medicine
2000;392(12):24-26
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Background: to assess the disturbances of blood gases in the patients with chronic obstructive pulmonary diseases (COPD), ventilation function was explored and blood gases were measured in 68 patients (mean age: 65.923.8) with COPD consisting of 40 males (58.8%) and 28 females (41.2%). Results: a large number of the patients hospitalized at late stages (32.35% at stage 1.25% at stage II and 42.5% at stage III). The main disturbance of blood gases in patients with COPD at stage I was a trivial PaO2 reduction with/ or without PaCO2 increase, on the contrary, the main disturbances of blood gases in those at stages II and III were severe exacerbation with a mixed feature (PaO2 reduction and PaCO2 increase). In the patients with COPD at stage I, PaO2 and PaCO2 did not significantly change (p>0.05); but there were significant disturbances in PaO2 and PaCO2 values in those at stages II and III (p<0.05). Conclusion: The result suggest that COPD should be identified, treated and managed at early stage because the chances of a fatal outcome are greater at late stage and, blood gases should be determined only at stage II and III COPD.
