Study on TORCH Infection Status of Pre-pregnant Women and Their Relationship with Pregnancy Outcome in Shanghai Hongkou District
10.3969/j.issn.1671-7414.2014.05.034
- VernacularTitle:上海虹口区孕前妇女TORCH三种病原体感染情况及与妊娠结局的关系分析
- Author:
Jie YU
;
Haiping WANG
;
Chunming FU
- Publication Type:Journal Article
- Keywords:
eugenics health examination;
TORCH test;
pregnancy outcome
- From:
Journal of Modern Laboratory Medicine
2014;(5):127-129
- CountryChina
- Language:Chinese
-
Abstract:
Objective The aim of study is to explore the TORCH infection status on the pre-pregnancy women and analyze the relationship with pregnancy outcome in Hongkou District,Shanghai,and provide the reference for the eugenic and superi-or nurture.Methods Enzyme linked immunosorbent assay (ELISA)was used to detect the specificity antibodies to Toxo-plasma (TOX),Rubelavirus (RUV),Cytomegalovirus (CMV)IgG and IgM in sera of the 3 500 pre-pregnant women in Hongkou District,Shanghai.Chi-square test was used for comparative analysis of the different rates.Results The positive rate of TOX-IgG,TOX-IgM,RV-IgG,CMV-IgG and CMV-IgM in pregnancy women from Hongkou district were 1.37%, 0.34%,89.7%,96.2% and 0.60% respectively.The total positive rate of TOX and (or)CMV IgM was 0.94%.According to age group,the results showed that TORCH infections with three pathogens associated with the pre-pregnancy women’s age,and the difference was statistically significant (χ2=102.9,P<0.01).The abnormal pregnancy rate of TORCH infec-tion-positive pregnancy women (25.0%,3/12)was higher than that of TORCH-negative pregnancy women (6.62%,27/408),and the difference was statistically significant (χ2 =4.43,P=0.04).Conclusion The infection opportunity of TORCH in pregnant women in Shanghai Hongkou district was obviously existent and the TORCH infection status could effect on pregnancy outcome.TORCH testing has important practical significance as a routine examination of the pre-preg-nancy healthy service.