Morphology Observation of A Family of May-Hegglin Abnormal Cell
10.3969/j.issn.1671-7414.2014.05.032
- VernacularTitle:一May-Hegglin异常家系细胞形态学观察
- Author:
Hongjie ZHANG
;
Feng GAO
- Publication Type:Journal Article
- Keywords:
May-Hegglin anomaly;
nclusion body
- From:
Journal of Modern Laboratory Medicine
2014;(5):119-122
- CountryChina
- Language:Chinese
-
Abstract:
Objective The morphological changes were observed in a pedigree with May-Hegglin anomaly cells.Methods Blood routine detection of abnormal May-Hegglin family members,peripheral blood cell Wright-Giemsa staining,and obser-vation of the white blood cell and platelet morphology.Made bone marrow smears of the proband,and megakaryocyte counts and classification.The proband peripheral blood leukocyte TEM examination were collected and analyzed by PCR sequen-cing.Results To reduce the May-Hegglin abnormal family blood platelet count in different degree,peripheral blood eosino-phil,eosinophilic inclusion visible form was not an alkaline cells,monocytes,neutrophils in body.Conclusion It’s provided valuable clues to diagnosis of morphological examination for May-Hegglin disorders.
