Serum Erythropoietin,Homocysteine Level Change and Its Significance in Ischemic Stroke Patients
10.3969/j.issn.1671-7414.2014.05.031
- VernacularTitle:缺血性脑卒中患者血清红细胞生成素与同型半胱氨酸水平改变及其意义
- Author:
Yan WU
;
Baishi WANG
- Publication Type:Journal Article
- Keywords:
ischemic stroke;
homocysteine;
erythropoietin
- From:
Journal of Modern Laboratory Medicine
2014;(5):117-119
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the episode of ischemic stroke in patients with serum homocysteine (Hcy),erythropoietin and its clinical significance (EPO)levels.Methods Detected 120 cases of first ischemic stroke patients serum Hcy,EPO lev-els and test results with 120 cases over the same period outpatient healthy compare.Used Logistic regression analysis and Pearson correlation analysis to determine the relationship between serum Hcy,EPO levels and ischemic stroke,ROC curve a-nalysis of clinical characteristics of Hcy and EPO.Results Serum Hcy,EPO level of ischemic stroke were respectively 23.1 ±12.6μmol/L and 32.4±11.2 mIU/L.The control level were respectively 10.4±2.8μmol/L and 17.6±5.2 mIU/L.Is-chemic stroke group were significantly higher.The results had statistical significance (P<0.05 or<0.01).Pearson correla-tion analysis showed that ischemic stroke serum Hcy levels and EPO levels were positively correlated (r=0.369,P<0.05). Logistic regression analysis showed that Ischemic stroke was positively related to serum Hcy level (P<0.05),and were not related to EPO (P>0.05).Conclusion The serum Hcy,elevated EPO levels associated with ischemic stroke.Serum Hcy is an independent risk factor of ischemic stroke.
