Current status of imipenem-resistant Pseudomonas aeruginosa infection and analysis of drug resistance in children
10.3969/j.issn.1673-4130.2015.07.005
- VernacularTitle:儿童耐亚胺培南铜绿假单胞菌的感染现状及药敏分析
- Author:
Yinghong HUANG
;
Yongqiang XIE
;
Huamin ZHONG
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
children：imipenem;
nosocomial infection;
drug resistance
- From:
International Journal of Laboratory Medicine
2015;(7):875-876
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the infection status and drug resistance of imipenem‐resistant Pseudomonas aeruginosa (PAE) isolated from the submitted specimens from children patients in our hospital between October 2012 to September 2013 for mastering the antimicrobial resistance status of Pseudomonas aeruginosa infection among children in Guangzhou and the occurrence situation of imipenem resistant strains .Methods The detection situation of Pseudomonas aeruginosa from infected children during this period was analyzed and the VITEK 2 Compact analyzer produced by the France bioMerieux company was used to identify the bacteria .The minimal inhibitory concentration(MIC) of imipenem resistant Pseudomonas aeruginosa to 11 kinds of antibiotics was detected .Results 161 strains of Pseudomonas aeruginosa were detected from 36 600 specimens ,including 24 strains(14 .9% ) of imipenem resistant Pseudomonas aeruginosa ,the positive strains were mainly originated from phlegmy (50 .3% ) ,the isolation was highest in ICU (27 .4% ) and NICU(21 .8% ) .The drug resistance rate of imipenem‐resistant P .aeruginosa was higher to ceftriax‐one sodium(91 .7% ) ,cefoperazone(29 .0% ) ,ceftazidime(29 .0% ) ,cefoperazone /shubatan(29 .0% ) and aztreonam (25 .0% ) .Con‐clusion Imipenem‐resistant Pseudomonas aeruginosa has the higher detection rate among children in this area and usually has re‐sistance to multiple antibiotics ,which should be paid more attention to and antibiotics should be rationally used .
