Relationship between the quantitative analysis of tissue diffusion and the level of serum creatinine in chronic renal allograft injury
10.3760/cma.j.issn.1004-4477.2014.10.015
- VernacularTitle:慢性移植肾损伤的组织弥散定量分析与血肌酐水平的相关性研究
- Author:
Ningning NIU
;
Ying TANG
;
Hongtao WU
;
Yang LIU
;
Jing LIU
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Kidney transplantation;
Creatinine;
Elasticity imaging techniques
- From:
Chinese Journal of Ultrasonography
2014;23(10):875-878
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the quantitative analysis of tissue diffusion of real-time elastography(RTE) in chronic renal allograft injury(CRAI) and the relationship between RTE and the level of serum creatinine(Cr).Methods Sixty-nine cases of allograft renal transplantation patients were detected by conventional ultrasound and RTE.According to the time after operation and Cr,they were divided into three groups:group A (in three months after operation and normal Cr,25 cases),group B (more than three months after operation and normal Cr,23 cases),and group C (more than three months after operation and high Cr,21 cases).The results were compared and analyzed.Results ①Contrast between group A and group B,there were differences on Cr and average ralative strain value(MEAN),area ratio of low-strain region (％ AREA),complexity (COMP),skewness (SKEW),(P ＜ 0.05).② In group B,there was correlation between Cr and ％AREA,MEAN,SKEW (r =0.682,P ＜0.05; r =0.628,P ＜0.05; r =-0.481,P ＜0.05).③To make ROC curve,MEAN has higher sensitivity (90.9％),COMP has higher specificity and accuracy (68.0％,81.8％).④ To apply the third result in group C,4 or 5 cases in 21 were abnormal.Conclusions There is a good correlation between the quantitative analysis of tissue diffusion and the level of serum creatinine.RTE can indirectly reflect CRAI,and it is a new method of ultrasonic to evaluate renal allograft function.
