Retrospective analysis on the diagnosis and treatment in 31 patients with clinical possible organizing pneumonia
10.3760/cma.j.issn.1673-4904.2014.31.006
- VernacularTitle:临床拟诊机化性肺炎31例诊疗的回顾性分析
- Author:
Yong SUN
;
Cunzhi LIN
;
Xiaoqian DING
;
Qiang WANG
;
Tao XU
- Publication Type:Journal Article
- Keywords:
Retrospective studies;
Organizing pneumonia;
Lung biopsy
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(31):15-18
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnosis and treatment of clinical possible organizing pneumonia.Methods The medical records of 31 patients with clinical probable organizing pneumonia were retrospectively analyzed.The clinical presentation,radiographic results and treatment were collected and analyzed.Results Thirty-one patients with non-response to antibiotics were preliminary diagnosed as organizing pneumonia.By percutaneous lung biopsy or transbronchial lung biopsy the tuberculosis,fungi,suppurative inflammation,lung cancer and other diseases were ruled out in 24 patients,and 7 patients were diagnosed by perfect effect of corticosteroids treatment.Twenty-one patients had typical CT findings.All the patients responded rapidly and completely to the administration of corticosteroids.Six patients relapsed after the reduction or stop of corticosteroid in a follow-up time of 6-25 months.Conclusions Non-response to antibiotics,the typical imaging findings and lung biopsy ruling out other diseases are important for diagnosing organizing pneumonia.Rapid response to administration of corticosteroids may be helpful to the diagnosis.Decreasing the dose of corticosteroid too early may cause recurrence of organizing pneumonia.